Codon Frequency Calculator

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Calculate the frequency and relative usage of each codon in a DNA/RNA sequence. Analyze codon bias and amino acid distribution.

Sequence Type *

Significant Figures

DNA/RNA Sequence (5' → 3') *

For DNA: A, T, G, C only. For RNA: A, U, G, C only. Sequence should be in-frame (length multiple of 3).

Organism (for codon bias reference)

Show Details

Show Amino Acid Summary

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Codon Frequency Analysis

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Total Codons

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codons

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Unique Codons

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out of 64

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Codon Diversity

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Most Frequent

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codon

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Codon Frequency Table

Each codon's count, frequency, and relative usage

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Distribution of amino acids in the sequence

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Identification of overrepresented and underrepresented codons

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Complete codon frequency information

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Understanding codon usage and bias

🧬 Biological Disclaimer: This calculator provides estimates for educational purposes. Codon usage varies between organisms and genes.